PHYLOGENETIC ANALYSIS OF INFLUENZA VIRUS TYPE A H1N1 NEURAMINIDASE GENE ISOLATED FROM HUMAN

Автор(и)

  • L. B. Zelena Kyiv National University of Technologies and Design; Zabolotny Institute of Microbiology and Virology, NAS of Ukraine, Україна
  • D. D. Parchevska Kyiv National University of Technologies and Design, Україна
  • N. V. Tkachuk T.H. Shevchenko National University “Chernihiv Colehium”, Україна
  • S. D. Zahorodnia Zabolotny Institute of Microbiology and Virology, NAS of Ukraine, Україна

Ключові слова:

influenza virus, neuraminidase, phylogenetic analysis

Анотація

The research was devoted to the study of influenza virus H1N1 neuraminidase gene genetic variability between isolates of various geographic localization and year of collection. The analysis of nucleotide sequence variability and phylogenetic analysis were performed using data from NCBI's Influenza Virus Resource and MEGA 10. The obtained results revealed clear differentiation between isolates of 2009 and the earlier collected ones. The level of genetic polymorphism was low among the isolates of 2009 and 98,6% of nucleotide sites were conservative.

Посилання

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Kumar S., Stecher G., Li M., Knyaz C., Tamura K. MEGA X: molecular evolutionary genetics analysis across computing platforms. Molecular biology and evolution. 2018. Vol. 35, No.6. P. 1547-1549. doi: 10.1093/molbev/msy096

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Опубліковано

2024-05-17