АНАЛІЗ ДИФЕРЕНЦІЙНО ЕКСПРЕСОВАНИХ ГЕНІВ І БІОЛОГІЧНИХ ПРОЦЕCІВ У ПЛАЦЕНТІ ЛЮДИНИ МІЖ ПЕРШИМ І ДРУГИМ ТРИМЕСТРОМ ФІЗІОЛОГІЧНОЇ ВАГІТНОСТІ

Автор(и)

  • Р. І. Джікірба КПІ ім. Ігоря Сікорського, Україна
  • М. Ю. Оболенська Інститут молекулярної біології і генетики НАН України, Україна

Ключові слова:

pregnancy complications, differential gene expression, gen-set enrichment analysis, placenta, enriched biological pathways

Анотація

In this study, a differential expression analysis on microarray was performed to compare the gene expression of 9 samples during the second trimester to 13 samples during the first trimester of normal pregnancy.  These results were used to perform gene-set enrichment analysis, the results of which demonstrated 260 enriched biological processes. Both the top 3 activated and inhibited biological processes were illustrated using cnetplot.

Посилання

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Опубліковано

2024-05-17