• К. М. Стогній КПІ ім. Ігоря Сікорського, Україна
  • О. П. Кузь КПІ ім. Ігоря Сікорського, Україна

Ключові слова:

optogenetics, opsins, biotechnology, neurons, biofuels


This article is devoted to optogenetics as a science combining physics and biology, its application  in biotechnology, and the latest research techniques. Various optogenetic tools are observed and the mechanisms of their work, as well as their possible application areas.


Ju D. W. Neuroscience: Canadian 1st Edition. Open Library Publishing Platform – Pressbooks for Ontario's Postsecondary Educators. URL: https://ecampusontario.pressbooks.pub/neurosciencecdn/.

Wimmer V. C., Lester H. A., Petrou S. ION CHANNELS | Ion Channel Mutations in Familial Epilepsy. Encyclopedia of Basic Epilepsy Research. 2009. С. 651–658. URL: https://doi.org/10.1016/b978-012373961-2.00146-6.

Lanyi J. K. 8.10 Light Capture and Energy Transduction in Bacterial Rhodopsins and Related Proteins. Comprehensive Biophysics. 2012. С. 206–227. URL: https://doi.org/10.1016/b978-0-12-374920-8.00816-x.

Optogenetic approaches in biotechnology and biomaterials / V. V. Reshetnikov та ін. Trends in Biotechnology. 2022. URL: https://doi.org/10.1016/j.tibtech.2021.12.007.

Chen Y., Xiong M., Zhang S.-C. Illuminating Parkinson's therapy with optogenetics. Nature Biotechnology. 2015. Т. 33, № 2. С. 149–150. URL: https://doi.org/10.1038/nbt.3140.

Optogenetics in Brain Research: From a Strategy to Investigate Physiological Function to a Therapeutic Tool / E. Montagni та ін. Photonics. 2019. Т. 6, № 3. С. 92. URL: https://doi.org/10.3390/photonics6030092.

Optogenetic regulation of engineered cellular metabolism for microbial chemical production / E. M. Zhao та ін. Nature. 2018. Т. 555, № 7698. С. 683–687. URL: https://doi.org/10.1038/nature26141.