• В. А. Ахмедова КПІ ім. Ігоря Сікорського, Україна

Ключові слова:

precision medicine, genetic test, biomarkers, combinatorial drug sensitivity platform


The article examines the important role of molecular biotechnology in the development of personalized medicine, ranging from the use of genetic tests to individualized therapy. Special attention is paid to the methods of genomic data analysis and their influence on the appointment of treatment, which makes it possible to effectively treat diseases in a unique way for each patient.


Artificial intelligence-based multi-omics analysis fuels cancer precision medicine / X. He et al. Seminars in Cancer Biology. 2022. URL: https://doi.org/10.1016/j.semcancer.2022.12.009 .

Recent advances in targeted therapies in acute myeloid leukemia / R.Bhansali., K.Pratz , C.Lai Journal of Hematology & Oncology. 2023. Vol. 16, no. 1. URL: https://doi.org/10.1186/s13045-023-01424-6 .

Clinical Evaluation of a Functional Combinatorial Precision Medicine Platform to Predict Patient-Specific Treatment Outcomes in Acute Myeloid Leukemia / E.Chow et al. Blood. 2023. Vol. 142, Supplement 1. P. 2276. URL: https://doi.org/10.1182/blood-2023-186251 .

The Human Genome Project. Genome.gov. URL: https://www.genome.gov/human-genome-project.

Topic: Precision Medicine Approaches in Cardiology: Personalized Therapies for Improved Patient Outcomes, a systematic review / Bamba H. et al. Current Problems in Cardiology. 2024. P. 102470. URL: https://doi.org/10.1016/j.cpcardiol.2024.102470 .

Towards precision medicine: advances in 5-hydroxymethylcytosine cancer biomarker discovery in liquid biopsy / C.Zeng et al. Cancer Communications. 2019. Vol. 39, no. 1. P. 12. URL: https://doi.org/10.1186/s40880-019-0356-x .

How personalised medicine will transform healthcare by 2030: the ICPerMed vision / A. M Vicente ., W.Ballensiefen , Jönsson J.-I. Journal of Translational Medicine. 2020. Vol. 18, no. 1. URL: https://doi.org/10.1186/s12967-020-02316-w

Functional precision medicine for pediatric cancers / M.Dolman, P. G Ekert . Nature Medicine. 2024. URL: https://doi.org/10.1038/s41591-024-02863-5 (date of access: 17.04.2024).

Machine Learning for Precision Medicine / S. J.MacEachern, N. D. Forkert. Genome. 2020. URL: https://doi.org/10.1139/gen-2020-0131(date of access: 18.04.2024).

Precision Medicine, AI, and the Future of Personalized Health Care / K. B. Johnson et al. Clinical and Translational Science. 2020. URL: https://doi.org/10.1111/cts.12884(date of access: 20.04.2024).

Artificial Intelligence in Cancer Research and Precision Medicine / B. Bhinder et al. Cancer Discovery. 2021. Vol. 11, no. 4. P. 900–915. URL: https://doi.org/10.1158/2159-8290.cd-21-0090 (date of access: 10.04.2024).

Artificial intelligence and machine learning in precision and genomic medicine / S.Quazi. Medical Oncology. 2022. Vol. 39, no. 8. URL: https://doi.org/10.1007/s12032-022-01711-1.

The Human Genome Project. Genome.gov. URL: https://www.genome.gov/human-genome-project.