ПОТЕНЦІАЛ ВИКОРИСТАННЯ ВТОРИННИХ МЕТАБОЛІТІВ TALAROMAYCES ACULEATUS У ФАРМАЦЕВТИЧНІЙ ПРОМИСЛОВОСТІ
Ключові слова:
Talaromyces aculeatus, secondary metabolites, pharmaceutical applications.Анотація
The article provides a review of current studies of the pharmaceutical potential of secondary metabolites produced by Talaromyces aculeatus. The analyzed compounds demonstrated a broad spectrum of biological activity, including antidiabetic, antitumor, anti-inflammatory, and antibacterial properties, indicating significant prospects for their application in drug development.
Посилання
Polyphasic taxonomy of the genus Talaromyces / N. Yilmaz та ін. Studies in Mycology. 2014. Т. 78. С. 175–341. URL: https://doi.org/10.1016/j.simyco.2014.08.001
Nicoletti R., Vinale F. Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces and Trichoderma Species. Marine Drugs. 2018. Т. 16, № 11. С. 408. URL: https://doi.org/10.3390/md16110408
Fruitful decade of fungal metabolites as anti-diabetic agents from 2010 to 2019: emphasis on α-glucosidase inhibitors / H. Hussain та ін. Phytochemistry Reviews. 2021. Т. 20, № 1. С. 145–179. URL: https://doi.org/10.1007/s11101-020-09733-1
Inducing Secondary Metabolite Production by Combined Culture of Talaromyces aculeatus and Penicillium variabile / Z. Zhang та ін. Journal of Natural Products. 2017. Т. 80, № 12. С. 3167–3171. URL: https://doi.org/10.1021/acs.jnatprod.7b00417
Anti-inflammatory polyketides from the endophytic fungus Talaromyces aculeatus A884 / J. Zhang та ін. Fitoterapia. 2025. Т. 187. С. 106926. URL: https://doi.org/10.1016/j.fitote.2025.106926
Nickavar B., Mehmannavaz M. Biocatalytic Hydroxylation of Progesterone by Penicillium aculeatum. Current Organocatalysis. 2024. Т. 11. URL: https://doi.org/10.2174/0122133372334969240902092741
A new antibacterial chromone derivative from mangrove-derived fungus Penicillium aculeatum (No. 9EB) / H. Huang та ін. Natural Product Research. 2017. Т. 31, № 22. С. 2593–2598. URL: https://doi.org/10.1080/14786419.2017.1283498
Antimicrobial Phenolic Bisabolanes and Related Derivatives from Penicillium aculeatum SD-321, a Deep Sea Sediment-Derived Fungus / X.-D. Li та ін. Journal of Natural Products. 2015. Т. 78, № 4. С. 844–849. URL: https://doi.org/10.1021/acs.jnatprod.5b00004