АНАЛІЗ ВІДОМИХ ШТАМІВ SHIGELLA SPP. ТА ПОЖИВНИХ СЕРЕДОВИЩ ДЛЯ ЇХ КУЛЬТИВУВАННЯ З МЕТОЮ ОТРИМАННЯ ПРЕПАРАТУ ПРОТИ ШИГЕЛЬОЗУ
Ключові слова:
Shigella, bacteriophages, phage therapy, Sfk20, cultivation.Анотація
Bacteriophage-based preparations are a promising alternative for the treatment of shigellosis due to increasing antibiotic resistance. The selection of optimal Shigella host strains (S. flexneri, S. sonnei, S. dysenteriae type 1) and a lytic bacteriophage Sfk20 ensures broad-spectrum activity. Optimization of cultivation conditions and nutrient media improves phage production efficiency.
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