БІОТЕХНОЛОГІЧНЕ ОТРИМАННЯ ПОЛІМЕРНОЇ ОСНОВИ ДЛЯ ВИРОБНИЦТВА ГІДРОГЕЛІВ ДЛЯ 3D-БІОДРУКУ
Ключові слова:
3D bioprinting, hydrogel, bacterial nanocellulose, bioniks.Анотація
This article examines the biotechnological synthesis of polymer matrices for biocompatible hydrogels. It focuses on producing bacterial nanocellulose and alginates, including modification strategies for extrusion-based 3D bioprinting. Findings show that microbial synthesis ensures high purity and controlled porosity, significantly boosting cell adhesion and proliferation for regenerative medicine.
Посилання
Gatenholm P., Klemm D. Bacterial nanocellulose as a renewable material for biomedical applications. MRS Bulletin. 2010. Vol. 35, no. 3. P. 208–213. URL: https://doi.org/10.1557/mrs2010.653.
Axpe E., Oyen M. Applications of alginate-based bioinks in 3D bioprinting. International journal of molecular sciences. 2016. Vol. 17, No. 12. P. 1976.
URL: https://doi.org/10.3390/ijms17121976.
Gungor-Ozkerim P. S., Inci I., Zhang Y. S., Khademhosseini A., Dokmeci M. R. Bioinks for 3D bioprinting: an overview. Biomaterials Science. 2018. Vol. 6, No. 5. P. 915–946.
URL: https://doi.org/10.1039/c7bm00765e.
Hospodiuk M., Dey M., Sosnoski D., Ozbolat I. T. The bioink: A comprehensive review on bioprintable materials. Biotechnology Advances. 2017. Vol. 35, No. 2. P. 217–239.
URL: https://doi.org/10.1016/j.biotechadv.2016.12.006.
Murphy S. V., Atala A. 3D bioprinting of tissues and organs. Nature Biotechnology. 2014. Vol. 32, No. 8. P. 773–785. URL: https://doi.org/10.1038/nbt.2958.
