ОСОБЛИВОСТІ МЕТАДАНИХ ДЛЯ ЗРАЗКІВ МАТЕРИНСЬКОЇ ЧАСТИНИ ПЛАЦЕНТИ ЗА УМОВ ФІЗІОЛОГІЧНОГО І УСКЛАДНЕНОГО ПРЕЕКЛАМПСІЄЮ ПЕРЕБІГУ ВАГІТНОСТІ
Ключові слова:
preeclampsia, placenta, GEO, metadata annotation, transcriptomicsАнотація
This study presents an overview of the GSE60438 dataset, which contains 125 placental samples obtained via cesarean section. Samples were grouped into control and preeclampsia cases, with further subdivision into early and late forms based on gestational age. Metadata including diagnosis, gestational age, maternal age, gravidity, parity, and infant sex were supplemented from original publications and systematically organized for comparative analysis.
Посилання
American College of Obstetricians and Gynecologists (ACOG). Preeclampsia. Clinical guidance. 2020. Available at: https://www.acog.org/clinical/clinical-guidance/practice- bulletin/articles/2020/06/gestational-hypertension-and-preeclampsia
Raymond, D., & Peterson, E. (2011). A critical review of early-onset and late-onset preeclampsia. Journal of Obstetrics and Gynaecology Canada, 33(12), 1256–1265. https://pubmed.ncbi.nlm.nih.gov/22018452/
Gene Expression Omnibus (GEO). National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/geo/
Rau, A., Marot, G., & Jaffrézic, F. (2013). Differential meta-analysis of RNA-seq data from multiple studies. arXiv preprint arXiv:1306.3636. https://arxiv.org/abs/1306.3636
GSE60438 Series Record. GEO Accession viewer. https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE60438
Our World in Data. Sex ratio at birth. Retrieved May 4, 2025, from https://ourworldindata.org/gender-ratio
Sex ratio at birth (male births per female births) / World Bank Gender Data Portal. (n.d.). World Bank Gender Data Portal. https://genderdata.worldbank.org/en/indicator/sp-pop-brth-mf?utm_source=chatgpt.com
Luo ZC, An N, Xu HR, Larante A, Audibert F, Fraser WD. The effects and mechanisms of primiparity on the risk of pre-eclampsia: a systematic review. Paediatr Perinat Epidemiol. 2007;21 Suppl 1:36–45. doi:10.1111/j.1365-3016.2007.00836.x
Hernandez-Diaz, S., Toh, S., & Cnattingius, S. (2009). Risk of pre-eclampsia in first and subsequent pregnancies: prospective cohort study. BMJ, 338, b2255. doi.org/10.1136/bmj.b2255
State Statistics Service of Ukraine. (2024). Women and Men in Ukraine – 2023 (p. 37). Retrieved from https://www.ukrstat.gov.ua/druk/publicat/kat_u/2024/01/W_M.pdf
Lamminpää, R., Vehviläinen-Julkunen, K., Gissler, M., & Heinonen, S. (2012). Preeclampsia complicated by advanced maternal age: a registry-based study on primiparous women in Finland 1997–2008. BMC Pregnancy and Childbirth, 12, 47. https://doi.org/10.1186/1471-2393-12-47
Galjaard, S., Ameye, L., Lees, C. C., Pexsters, A., Bourne, T., Timmerman, D., & Devlieger, R. (2019). Sex differences in fetal growth and immediate birth outcomes in a low-risk Caucasian population. Biology of Sex Differences, 10(1). https://doi.org/10.1186/s13293-019-0261-7
