СУЧАСНІ ПІДХОДИ ВИКОРИСТАННЯ БАКТЕРІОФАГІВ У БІОТЕХНОЛОГІЧНИХ ЦІЛЯХ
Ключові слова:
bacteriophages, phage therapy, phage engineering, phage display, medical biotechnologyАнотація
Despite of the development of various antibacterial drugs, the emergence of multidrug-resistant bacteria is a major problem today. Bacteriophages are agents of antibacterial treatment and have such advantages: specificity of lysis of target bacteria and low toxicity. Currently, there are a wide range of applications of these biological agents in the field of medicine, pharmacy and biotechnology.
Посилання
Phage-derived antibacterials: harnessing the simplicity, plasticity, and diversity of phages / B.-o. Kim et al. Viruses. 2019. Vol. 11, no. 3. P. 268. URL: https://doi.org/10.3390/v11030268.
The biotechnological application of bacteriophages: what to do and where to go in the middle of the post-antibiotic era / S. J. Jo et al. Microorganisms. 2023. Vol. 11, no. 9. P. 2311. URL: https://doi.org/10.3390/microorganisms11092311.
Santos S. B., Azeredo J. Bacteriophage-based biotechnological applications. Viruses. 2019. Vol. 11, no. 8. P. 737. URL: https://doi.org/10.3390/v11080737.
Bacteriophage bioengineering: a transformative approach for targeted drug discovery and beyond / L. Cui et al. Pathogens. 2023. Vol. 12, no. 9. P. 1179. URL: https://doi.org/10.3390/pathogens12091179.
Gordillo Altamirano F. L., Barr J. J. Phage therapy in the postantibiotic era. Clinical Microbiology Reviews. 2019. Vol. 32, no. 2. URL: https://doi.org/10.1128/cmr.00066-18.
Rational identification of a colorectal cancer targeting peptide through phage display / D. Ferreira et al. Scientific Reports. 2019. Vol. 9, no. 1. URL: https://doi.org/10.1038/s41598-019-40562-1.
Enhanced antibacterial activity of Acinetobacter baumannii bacteriophage ØABP-01 endolysin (LysABP-01) in combination with colistin / R. Thummeepak et al. Frontiers in Microbiology. 2016. Vol. 7. URL: https://doi.org/10.3389/fmicb.2016.01402.
Retargeting R-type pyocins to generate novel bactericidal protein complexes / S. R. Williams et al. Applied and Environmental Microbiology. 2008. Vol. 74, no. 12. P. 3868–3876. URL: https://doi.org/10.1128/aem.00141-08.
