• N. O. Snihur Igor Sikorsky Kyiv Polytechnic Institute, Ukraine
  • P. S. Kovalchuk Igor Sikorsky Kyiv Polytechnic Institute, Ukraine


For a long period of time, 2D and 3D cultures, model animals have been used for experiments, but in recent years, organ-on-chip (OoC) technology has
become more popular and it is rapidly gaining significant research attention (figure 1). The combination of the "laboratory-on-chip" with the methods of cell biology moderates the research methods and makes it possible to design physiological processes of the human body on models of multicellular human organs in vitro. The aim of this article is to overview the most interesting and important OoCs, which recreate brain structures, the progress of creating those chips and their classification.


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