SYNERGISTIC EFFECT ON YEAST OF A MIXTURE OF ACINETOBACTER CALCOACETICUS IMV B-7241 SURFACTANTS WITH ANTIFUNGAL DRUGS
Анотація
The number of publications devoted to the study of Candida genus representatives causative agents of nosocomial infectious diseases is increasing every year. This is due, first of all, to the spread of their resistant forms, arising against the background of prolonged use of broad-spectrum antibiotics, immunosuppressive therapy, and prolonged catheterization of patients [1]. Compared to antibacterial agents, the number of antifungal agents is much smaller, and most clinical isolates of the genus Candida (in particular C. albicans, C. tropicalis and C. glabrata) are resistant to azoles, which are currently the most common to fungal infections treated [2].
Посилання
Singh D. K., Tóth R., Gácser A. Mechanisms of pathogenic Candida species to evade the host
complement attack Front Cell Infect Microbiol. 2020. Vol.10, No 94.
Bhattacharya S., Sae-Tia S., Fries B. C. Candidiasis and mechanisms of antifungal resistance.
Antibiotics (Basel). 2020. Vol. 9, No 6. P. 312.
Pirog T. P., Sidor I. V., Lutsai D. A. Calcium and magnesium cations influence on antimicrobial and antiadhesive activity of Acinetobacter сalcoaceticus ІMV B-7241 surfactants. Biotechnologia Acta. 2016. Vol. 9, No 6. P. 50-57.
Pirog T. P., Lutsay D. A., Shevchuk T. A., Iutynska G. O. Synthesis and biological activity of Acinetobacter calcoaceticus IMV B-7241 surfactants depending on monovalent cations content in cultivation medium. Microbiol. Zh. 2021. Vol. 83, No 2. P. 20–31